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Bi-Estroderm Topical Cream 4 oz - Karma Flo
Bi-Estroderm Topical Cream 4 oz - Karma Flo

Bi-Estroderm Cream (Estriol + Estradiol)

Regular price $24.00 Sale

Karma Flo Bi-Estroderm is a balanced bioidentical estrogen cream combining estriol and estradiol in an 80/20 ratio. Designed for topical use, it provides targeted hormone support with the convenience of a metered pump. Made in the USA, fragrance-free, and free from parabens and animal products.

Karma Flo Bi-Estroderm Cream contains a balanced combination of two bioidentical estrogens: estriol (E3) and estradiol (E2) in an 80/20 ratio. Each metered pump delivers 1 mg of estriol and 0.25 mg of estradiol. Estriol is the weakest of the three primary estrogens and is often favored for its gentler profile, while estradiol is the primary estrogen produced by the ovaries during reproductive years.

This topical formula is absorbed directly into the circulation, bypassing the liver. The cream is intended to support healthy estrogen levels as part of a hormone balance regimen, particularly during perimenopause and menopause when natural estrogen production declines.

Key Features:

  • 1 mg Estriol (E3) + 0.25 mg Estradiol (E2) per pump
  • 80/20 balanced ratio
  • Available in 4 oz and 2 oz metered-pump containers
  • Fragrance-free, paraben-free, no animal testing or animal products
  • Made in the USA under FDA GMP guidelines

Suggested Use:

Apply one full pump 1-2 times per day to the chest, abdomen, inner arms, or thighs, rotating sites. Use as directed or as recommended by your healthcare practitioner.

Important: This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease. Keep out of reach of children. For external use only. Do not use if pregnant, may become pregnant, or lactating unless directed by a healthcare professional.

Frequently Asked Questions

What is the difference between estriol and estradiol?
Estradiol (E2) is the primary and most potent estrogen produced by the ovaries. Estriol (E3) is a weaker estrogen. Karma Flo Bi-Estroderm uses an 80/20 ratio of estriol to estradiol for a balanced topical formula.
How should I apply Bi-Estroderm?
Apply one full pump to clean skin on the chest, abdomen, inner arms, or thighs. Rotate sites with each application. Allow the cream to absorb before covering the area.
Is this product the same as prescription estrogen?
Bi-Estroderm contains USP-grade bioidentical estriol and estradiol. It is an over-the-counter topical product and is not a prescription medication.
Can I use Bi-Estroderm together with progesterone cream?
Many individuals use estrogen and progesterone support together as part of a balanced approach. Consult your healthcare professional for personalized guidance.
Is the formula gentle on skin?
Yes. The cream is fragrance-free, paraben-free, and formulated without animal-derived ingredients. Discontinue use if any irritation occurs.